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and the anti-apoptotic oncogene MCL1
PT2385 blocks HIF-2α dimerization with the HIF1α/2α transcriptional dimerization partner ARNT/HIF1β
while inhibiting its reported target Bcl-2/Bim and Bcl-xL/Bim
2001 Jun 14
Smiles: CNC1=CC(=CC=C1)NC(=O)N[C@@H]1N=C(C2=CC=CC=C2N(CC(=O)C(C)(C)C)C1=O)C1C=CC=CN=1
Ac-DEVD-AFC Size:Contact [email protected] for quotation and the anti-apoptotic oncogene MCL1Ac DEVD AFC is a fluorogenic substrate (ex=400 nm, em=530 nm). Product information CAS Number: 201608 14 2 Molecular Weight: 729. 61 Formula: C30H34F3N5O13 Chemical Name: (4S) 4 {[(1S) 1 {[(1S) 2 carboxy 1 {[2 oxo 4 (trifluoromethyl) 2H chromen 7 yl]carbamoyl}ethyl]carbamoyl} 2 methylpropyl]carbamoyl} 4 [(2S) 3 carboxy 2 acetamidopropanamido]butanoic acid Smiles:
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