BMS-378806 Catalog No.:M10727-10 Smiles: COC(=O)N(CC1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F)[C@H]1C[C@@H](CC)N(C2=CC=C(C=C21)C(F)(F)F)C(=O)OCC

Smiles: COC(=O)N(CC1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F)[C@H]1C[C@@H](CC)N(C2=CC=C(C=C21)C(F)(F)F)C(=O)OCC

[Epub ahead of print] PubMed PMID: 32029439

InChiKey: ZLHFONARZHCSET-UHFFFAOYSA-N

a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity

Colo205-R cells (IC50: >10 μM) are >300-fold more resistant to Ingenol Mebutate than parental Colo205-S cells

BMS-378806 Catalog No.:M10727-10 Smiles: COC(=O)N(CC1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F)[C@H]1C[C@@H](CC)N(C2=CC=C(C=C21)C(F)(F)F)C(=O)OCCBMS 378806 is a small molecule that inhibits the first step of HIV 1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It binds the exterior envelope glycoprotein gp120 (Kd= 21. 1 nM; Ki = 24. 9 nM), blocking the conformational change that occurs with CD4 binding and preventing fusion of the viral and target cell membranes. Product information CAS Number: 357263 13 9 Molecular Weight: 406. 43 Formula: C22H22N4O4 Chemical