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In cell-free kinase assays Sotrastaurin (AEB071) inhibits PKC
Epub 2017 Sep 18
J Glaucoma
Molecular Weight: 420
Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders
Triclabendazole niliprole In cell-free kinase assays SotrastaurinTriclabendazole is an anthelmintic and fasciolicidal, binding to beta tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and
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