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686770-61-6
Overstreet DH
Nathanael S
3S)-2-{[(2S)-1-[(2S)-2-[(2S)-6-[(2S)-2-{[(benzyloxy)carbonyl]amino}-5-[(diaminomethylidene)amino]pentanamido]-2-[(2S)-3-(4-hydroxyphenyl)-2-[(pyridin-3-yl)formamido]propanamido]hexanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-methylpentanoic acid
the enzyme which catalyzes the conversion of HMG-CoA to mevalonate
TAS-103 dihydrochloride Size:Solid 2 mg 686770-61-6TAS 103, also known as BMS 247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS 103 has been reported to be a potent topoisomerase II poison. TAS 103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0. 05). The combination with CDDP augmented the antitumor activity of TAS 103 (p<0. 05), indicating that CDDP is one of the most potent candidates
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