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O=C(CC1=CC=C(C=N1)C1C=CC(=CC=1)OCCN1CCOCC1)NCC1C=CC=CC=1
It shows more than 100-fold selectivity for mTOR relative to PI3Kα
CAS Number: 2070015-31-3
Single intraperitoneal doses of 10 mg/kg Trichostatin A in nontransgenic and spinal muscular atrophy (SMA) model mice results in increased levels of acetylated H3 and H4 histones and modest increases in survival motor neuron (SMN) gene expression
5-trimethoxybenzoate
NH2-C4-NH-Boc 735 O=C(CC1=CC=C(C=N1)C1C=CC(=CC=1)OCCN1CCOCC1)NCC1C=CC=CC=1NH2 C4 NH Boc (compound 15) is a PROTAC linker, which refers to the Alkyl ether composition. NH2 C4 NH Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information CAS Number: 68076 36 8
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