UK-370106 is found to be inactive (IC50 > 100 µM) vs zinc metalloproteases PCP and TACE and possesses the following inhibitory potencies vs MMP-2 (IC50 of 34
Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages
Smiles: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
HA130 is a selective autotaxin (ATX) inhibitor with an IC50 of 28 nM
Smiles: CC1=C([C@@H](OC2=CC(O)=CC=C21)C1C=CC(=CC=1)OCCN1CCCCC1)C1C=CC(O)=CC=1
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 Size:Contact [email protected] for quotation UK-370106 is found to beN (azide PEG3) N' (Mal PEG4) Cy5 is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2107273 74 3 Molecular Weight: 962. 57 Formula: C50H68ClN7O10 Chemical Name: 2 [(1E,3E) 5 [1 (2 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}ethyl) 3,3 dimethyl 2,3 dihydro 1H indol 2 ylidene]penta 1,3 dien 1 yl] 1 (14 {[2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethyl]carbamoyl} 3,6,9,12 tetraoxatetradecan 1 yl) 3,3 dimethyl