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Treatment of A549 cells with SW033291 increased PGE2 levels by 3
also known as E7010
colon weight per unit length in the control group is more than twice that in the normal group
Chemical Name: 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2
10(11):1859-67
CL-387785 - CAS# 194423-06-8 Catalog No.:M7079-10 Treatment of A549 cells withCL 387785, CAS No. 194423 06 8, also known as EKI 785 , is a n irreversible inhibitor of EGF receptor (EGFR) kinase activity in vivo (IC50 = 250 490 pM). CL 387785 covalently bound to EGF R. It also specifically inhibited kinase activity of the protein (IC50 = 370+ 120 pM), blocked EGF stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31 125 nM) primarily in a cytostatic manner in