3, 5, 6, 7, 8, 3', 4'-Heptemthoxyflavone N1-IN-1 CAS Number: 1800405-30-4

CAS Number: 1800405-30-4

Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator

C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](OC(C)=O)[C@H](C[C@@]43C)N3CC[N+](C)(C)CC3)[C@@H]1C[C@@H]([C@@H]2OC(C)=O)N1CC[N+](C)(C)CC1

42 nM (Flt4)

10 mg/kg) yields the plasma AUC

3, 5, 6, 7, 8, 3', 4'-Heptemthoxyflavone N1-IN-1 CAS Number: 1800405-30-43,5,6,7,8,3',4' heptamethoxyflavone, a flavonoid in C. unshiu peels, exhibits anti tumor initiating effect and Anti neuroinflammatory activity. 3,5,6,7,8,3',4' heptamethoxyflavone inhibits collagenase activity and increased type I procollagen content in HDFn cells. 3,5,6,7,8,3',4' heptamethoxyflavone induces brain derived neurotrophic factor (BDNF) expression via cAMP ERK CREB signaling and reduces phosphodiesterase activity in C6 cells. Product