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This gene encodes the inducible isozyme
The encoded protein is involved in linking the actin cytoskeleton with vesicle formation
thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity
lymphatic vessel
and epithelial/endothelial monolayer permeability due to its large size
Human FGL1 qPCR Reagents This gene encodes the inducibleHepassocin, also known as hepatocyte derived fibrinogen related protein 1 (HFREP 1) and Fibrinogen Like Protein 1 (FGL1), is a liver specific secreted protein belonging to the fibrinogen superfamily. Human Hepassocin FGL1 is a secreted homodimer consisting of 312 amino acids (aa) with a 22 aa signal sequence and a 290 aa mature protein. Human Hepassocin FGL1 binds LAG 3 through its fibrinogen like domain independently of MHC class II. Hepassocin FGL1
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