63 μM in vero E6 cells
It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram-positive bacteria found in skin infections including Staphylococcus aureus strains
Testing of INCB024360-analog in mice demonstrated pharmacodynamic inhibition of IDO
53(20):7287-95
InChi: InChI=1S/C20H30O5/c1-12-4-7-16-19(2
18α-Glycyrrhetinic acid - CAS# 1449-05-4 Catalog No.:M12685-10 63 μM in vero E618 Glycyrrhetinic acid, a diet derived compound, is an inhibitor of NF kB and an activator of proteasome, which serves as pro longevity and anti aggregation factor in a multicellular organism. 18 Glycyrrhetinic acid induces apoptosis. Product information CAS Number: 1449 05 4 Molecular Weight: 470. 68 Formula: C30H46O4 Chemical Name: (2S, 4aS, 6aS, 6bR, 8aR, 10S, 12aS, 12bR, 14bS) 10 hydroxy 2, 4a, 6a, 6b, 9, 9, 12a heptamethyl 13 oxo 1, 2, 3, 4, 4a,