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InChi: InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11
InChiKey: JGQPZPLJOBHHBK-UFXYQILXSA-N
is a novel inhibitor of the interaction between ß-catenin and T cell factor 4 (Tcf4)
BAF312 is currently in clinical trials to treat multiple sclerosis
20(3):e138
Perifosine Size:2mg solid InChi: InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11Perifosine is an orally active alkyl phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti apoptotic mitogen activated protein kinase (MAPK) pathway and modulates the balance between