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ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18
Siramesine involves lysosomal leakage and oxidative stress
14-4-2-12)21-10-9(18)8(17)7(16)6(5-15)20-10/h6-10
a second generation bisphosphonate and synthetic analog of pyrophosphate with bone anti-resorption activity
the neuroprotective effect of this agent is less pronounced in the hippocampal CA1 sector
Lazertinib Catalog No.:M13413-2 ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18Lazertinib (YH25448,GNS 1480) is a potent, highly mutant selective and irreversible EGFR TKI with IC50 values of 1. 7 nM, 2 nM, 5 nM, 20. 6 nM and 76 nM for Del19 T790M, L858R T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4. Product information CAS Number: 1903008 80 9 Molecular Weight: 554. 64 Formula: C30H34N8O3 Chemical Name: N {5 [(4 {4 [(dimethylamino)methyl] 3 phenyl 1H pyrazol 1
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