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PubMed PMID: 25074280
in mice carrying p53-deficient and -proficient human xenografts
Smiles: CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
CAS Number: 910808-11-6
InChi: InChI=1S/C25H16O9/c1-12(26)31-15-4-7-19-21(10-15)33-22-11-16(32-13(2)27)5-8-20(22)25(19)18-6-3-14(23(28)29)9-17(18)24(30)34-25/h3-11H
Edoxaban (tosylate monohydrate) Size:Solid 2 mg PubMed PMID: 25074280Edoxaban is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and noncentral nervous system systemic
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