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ABT-199 inhibits the growth of BCL-2–dependent human hematological tumors in vivo and spares human platelets as a single agent or in combination with rituximab and bendamustine
CAS Number: 1527473-33-1
PF04494700
MGCD0103 (170 mg/kg for 2HBr salt
EHT 1864 (oral administration) displays good tolerability
GW3965 HCl - CAS# 405911-17-3 size:2mg solid ABT-199 inhibits the growth ofGW3965 HCl, CAS No. 405911 17 3, is a liver X receptor agonist. GW3965 represses the production of pro inflammatory cytokines by murine mast cells. GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro. GW3965 dose dependently regulates lps mediated liver injury and modulates posttranscriptional TNF alpha
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