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RNA splicing inhibitor
The Quad Pill was approved by the FDA in August 2012 for use in the United States and is owned by Gilead Sciences
Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system
Srikanth Appikonda
Water: 9 mg/mL(61
(3S, 4S)-PF-06459988 03 (methanesulfonate) RNA splicing inhibitor(3S, 4S) PF 06459988 is the S enantiomer of PF 06459988 with less active. PF 06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF 06459988 has excellent selectivity against EGFR wild type while possessing a minimally reactive electrophile that reduces the propensity of off target labeling. Product information CAS Number: 1858291 14 1 Molecular Weight: 431. 88 Formula: C19H22ClN7O3 Chemical Name: 1
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