AZD0156 '-Di-O-methylellagic acid-4'-O-β-D-glucopyranoside InChiKey: WXJFKKQWPMNTIM-VWLOTQADSA-N

InChiKey: WXJFKKQWPMNTIM-VWLOTQADSA-N

Tasquinimod was used at 1-10 µM final concentration in various in vitro assays

5-8 hours) blocks the expression of tissue factor induced by UII in endothelial cells

24-48 h) increase of LDH leakage in both concentration- and time-dependent manner in HepG2 cells

Smiles: CC(C)(O)/C(/C)=C/C(=O)O[C@@H]1[C@H]2C3(OC[C@]42[C@H]([C@@H](O)[C@@H]3O)[C@@]2(C)CC(=O)C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C(C)[C@@H]2C[C@H]4OC1=O)C(=O)OC

AZD0156 '-Di-O-methylellagic acid-4'-O-β-D-glucopyranoside InChiKey: WXJFKKQWPMNTIM-VWLOTQADSA-NAZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0. 58 nM. AZD0156 inhibits the ATM mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis. Product information CAS Number: 1821428 35 6 Molecular Weight: 461. 56 Formula: C26H31N5O3 Chemical Name: 8 {6 [3 (dimethylamino)propoxy]pyridin 3 yl} 3 methyl 1 (oxan 4 yl) 1H,2H,3H imidazo[4,5 c]quinolin 2 one