PXS-5120A 8784 inhibition at 24 hours (51%-78%)

inhibition at 24 hours (51%-78%) is almost comparable with that seen at 4 hours

Chemical Name: 3-(5-hydroxy-1-oxo-2

30(5):574-7

7-²H₄)pyrazolo[1

Fosfomycin sodium (MK-0955 sodium) is a blood-brain barrier penetrating

PXS-5120A 8784 inhibition at 24 hours (51%-78%)PXS 5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase like 2 3 (LOXL2 3) with anti fibrotic activity. PXS 5120A is >300 fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8. 4) over LOXL (pIC50 of 5. 8). Product information CAS Number: 2125955 70 4 Molecular Weight: 481. 97 Formula: C22H25ClFN3O4S Chemical Name: 1 [(2Z) 4 amino 2 fluorobut 2 en 1 yl] 3 [3 (dimethylsulfamoyl)phenyl] 2 methyl 1H indole 5 carboxylic acid