GSK-843 - CAS# 1601496-05-2 1137 575 inhibits beta-amyloid peptide production

575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

62(15):7146-7159

2015 Sep 21

Formula: C15H13NO2

Chemical Name: 2-(dimethylamino)-N-(6-oxo-5

GSK-843 - CAS# 1601496-05-2 1137 575 inhibits beta-amyloid peptide productionGSK 843 (GSK'843) is a receptor interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8. 6 nM, and inhibits kinase activity with an IC50 of 6. 5 nM. Product information CAS Number: 1601496 05 2 Molecular Weight: 377. 49 Formula: C19H15N5S2 Synonym: GSK'843 Chemical Name: 3 (1, 3 benzothiazol 5 yl) 7 (1, 3 dimethyl 1H pyrazol 5 yl)thieno[3, 2 c]pyridin 4 amine Smiles: