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The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target
In the Ruxolitinib group
and inhibition of cancer cell growth
1999 Nov 5
124(6):1463-9
Dihexa - CAS# 1401708-83-5. CAS# 1401708-83-5 043 The E3 ubiquitin-ligase Bmi1/Ring1A controlsDihexa, CAS No. 1401708 83 5, also known as PNB 0408, N hexanoic Tyr Ile (6) aminohexanoic amide, CAS No. 1401708 83 5, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c Met. Dihexa has been found to potently improve cognitive function in animal models of Alzheimer's disease like mental impairment. In an assay of neurotrophic activity,
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