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MV4-11ITD/D835
Smiles: COC1=CC=CC(=C1)NC1=NC=NN2C=CC(CN3C[C@@H](O)[C@H](N)CC3)=C21
2 μM for VPS4B and p97
thereby inhibiting its activity as a protein that activates the ubiquitin-like protein UFM1 to UFMylate proteins
with a subnanomolar Kd toward PI3Kα and mTOR (0
CL2A Abd-7 MV4-11ITD/D835CL2A is a claevable complicated PEG8 and triazole containing PABC peptide mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker. Product information CAS Number: 2616704 22 2 Molecular Weight: 1062. 21 Formula: C50H79N9O16 Chemical Name: N [(1 {26 [2 ({[(1S) 5 amino 1 {[4
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