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InChiKey: FBOUYBDGKBSUES-VXKWHMMOSA-N
Smiles: CC1=CC=CC2=C1C=CC1=C2C(=O)C2OCC(C)C=2C1=O
Chrysophanic acid (Chrysophanol) treatment in SNU-C5 cells inhibits EGF-induced phosphorylation of EGFR and suppresses activation of downstream signaling molecules
24)25)18-19(27)28-11-29-32(17)18/h4-5
Study of Na
GCN2-IN-6 L246) InChiKey: FBOUYBDGKBSUES-VXKWHMMOSA-NGCN2 IN 6 (Compound 6d) is a potent, and orally available GCN2 inhibitor confirmed by in house enzymatic (IC50 of 1. 8 nM) and cellular assays (IC50 of 9. 3 nM). GCN2 IN 6 is also a eIF2 kinase PERK inhibitor with an IC50 of 0. 26 nM (in enzymatic assay) and 230 nM (in cells). Product information CAS Number: 2183470 09 7 Molecular Weight: 485. 29 Formula: C19H12Cl2F2N4O3S Chemical Name: N {3 [2 (2 aminopyrimidin 5 yl)ethynyl] 2,4 difluorophenyl} 2,5