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0 nM and [3H]-inositolphosphate accumulation with an IC50 of 5
Prolonged exposure to (R)-bicalutamide generates a LNCaP subclone with alteration of mitochondrial genome
PMID: 31570196
Compound C
InChiKey: WPTTVJLTNAWYAO-KPOXMGGZSA-N
KN-93 ies 0 nM and [3H]-inositolphosphate accumulationKN 93 free base is a CaMKII inhibitor. KN 93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN 93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN 93 ameliorates levodopa induced dyskinesia in a rat model of Parkinson's disease. KN 93 protects rat cerebral cortical neurons from N methyl D aspartic acid induced injury. Product information CAS Number: 139298