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Molecular Weight: 244
is a potent and selective Pyruvate kinase M2 (PKM2) activator with EC50 ~38 nM
three times a week
which are required for MLL1 mediated leukemogenesis
is a chemical probe for PRMT5
ATB-346 - CAS# 1226895-20-0 Catalog No.:M60414-2S Molecular Weight: 244ATB 346, CAS No. 1226895 20 0, is anti inflammatory agent, which is structurally an analogue of naproxen. ABT 346 exhibits anti inflammatory properties similar to naproxen, but with substantially reduced gastrointestinal toxicity. ATB 346 suppressed colonic prostaglandin synthesis and whole blood thromboxane synthesis as effectively as naproxen, but did not induce any gastrointestinal injury. ATB 346 exerts superior chemopreventive effects to those of
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