K-Ras ligand-Linker Conjugate 1 pyrrole A Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1=NC2=CC=CC=C2N=C1NC1=CC2=NSN=C2C=C1

Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1=NC2=CC=CC=C2N=C1NC1=CC2=NSN=C2C=C1

Chemical Name: 5-beta-Cholest-7-en-6-one

Oral pharmacokinetics and food interaction of the leukotriene D4 receptor antagonist verlukast

Smiles: CC(O)(CS(=O)(=O)C1C=CC(F)=CC=1)C(=O)NC1=CC(=C(C=C1)C#N)C(F)(F)F

CAS Number: 40246-10-4

K-Ras ligand-Linker Conjugate 1 pyrrole A Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC1=NC2=CC=CC=C2N=C1NC1=CC2=NSN=C2C=C1K Ras ligand Linker Conjugate 1 incorporates a ligand for K Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 1 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information Molecular Weight: 826. 94 Formula: C43H54N8O9 Chemical Name: benzyl (2S) 2 (cyanomethyl) 4 (2