JH-X-119-01 roxylin Chemical Name: 1-bromo-2-(2-methoxyethoxy)ethane

Name: JH-X-119-01 roxylin Chemical Name: 1-bromo-2-(2-methoxyethoxy)ethane
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SKU: 42180891328
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SKU: 42180891328

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Description

Chemical Name: 1-bromo-2-(2-methoxyethoxy)ethane

JH-X-119-01 roxylin Chemical Name: 1-bromo-2-(2-methoxyethoxy)ethaneJh X 119 01 is a novel potent and selective interleukin 1 receptor associated kinases 1 (IRAK1) inhibitor. JH X 119 01 irreversibly labels IRAK1 at C302. This compound exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88. Cotreatment of JH X 119 01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems. Product information CAS Number:

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